Economy Wolverine Research Stack
Storage: Keep refrigerated upon reconstitution
$110.00
Economy Wolverine Research Stack
BPC-157 | TB-500 Synergistic Complex
The 4Balance Codex: The Dual-Vector Approach to Accelerated Musculoskeletal Regeneration and Angiogenesis.
Product Overview
The Economy Wolverine Research Stack is a foundational dual-peptide system designed for the investigation of accelerated musculoskeletal recovery and soft tissue repair. This bundle integrates the potent angiogenic and cytoprotective properties of BPC-157 (5mg) with the actin-regulating and cell-migratory capabilities of TB-500 (5mg). It is the established standard for researchers studying the synergistic molecular pathways involved in rapid tendon, ligament, and muscle regeneration in civilian and athletic models.
Total Active Content: 10mg Lyophilized Peptides Components: BPC-157 (5mg), TB-500 (5mg) Research Focus: Tendon/Ligament Repair, Muscle Recovery, Angiogenesis, Inflammation Modulation
Mechanism of Action: Synergistic Repair Pathways
The "Wolverine" protocol addresses the two primary bottlenecks in healing poorly vascularized tissue: lack of blood supply and slow cellular recruitment.
Vascularization & Cytoprotection (BPC-157): A synthetic pentadecapeptide derived from human gastric signaling proteins. In research models involving avascular tissues (like tendons and ligaments), BPC-157 acts as a potent stimulus for the Vascular Endothelial Growth Factor (VEGF) pathway and modulates the nitric oxide (NO) system. This promotes rapid angiogenesis (formation of new capillaries), delivering essential oxygen and nutrients to the injury site and protecting existing cells from oxidative stress.
Cellular Migration & Actin Sequestration (TB-500): A synthetic fragment of the naturally occurring protein Thymosin Beta-4 (Tβ4). Its primary mechanism is the sequestration of G-actin, a vital component of the cellular cytoskeleton. By regulating actin polymerization, TB-500 significantly increases the migratory speed of endothelial cells and keratinocytes, recruiting repair cells to the site of damage faster. It also exhibits potent anti-inflammatory properties and reduces fibrotic scar tissue formation.
Research Applications
In the 4Balance Research Array, this stack is utilized to study total tissue repair kinetics.
Acute Musculoskeletal Injury: Used to investigate accelerated healing in models of muscle tears, sprains, and fractures by combining increased blood flow (BPC-157) with rapid cellular recruitment (TB-500).
Tendon and Ligament Pathologies: Research indicates that BPC-157 enhances fibroblast proliferation in tendons, while TB-500 assists in organizing collagen deposition, potentially leading to structurally stronger repairs with less scar tissue.
Chronic Inflammation: Studied for the ability to modulate chronic inflammatory states that impede healing, transitioning the tissue environment from inflammatory to regenerative.
Technical Specifications
Vial 1: BPC-157 (Body Protection Compound)
Mass: 5mg
Sequence Length: 15 Amino Acids
Role: Angiogenic Signaling Agent
Vial 2: TB-500 (Thymosin Beta-4 Frag)
Mass: 5mg
Mechanism: Actin-sequestering domain
Role: Cellular Migration Enhancer
General Storage: Store all lyophilized vials at -20°C. Once reconstituted with bacteriostatic water, store at 4°C and use within established stability timelines for each respective peptide.
References
Sikiric, P., et al. (2010). The beneficial effect of BPC 157, a gastric pentadecapeptide, on tendon healing. Journal of Physiology and Pharmacology.
Chang, C. H., et al. (2011). Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts. Molecules.
Goldstein, A. L., et al. (2012). Thymosin β4: actin-sequestering protein moonlights to repair injured tissues. Trends in Molecular Medicine.
Philp, D., et al. (2003). Thymosin beta4 and a synthetic peptide containing its actin-binding domain promote dermal wound repair. Wound Repair and Regeneration.
Hsieh, M. J., et al. (2017). Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation. Journal of Molecular Medicine.
DISCLAIMER: FOR RESEARCH USE ONLY. This product bundle is a collection of laboratory reagents intended strictly for in-vitro research and development. They are not for human consumption, veterinary use, or therapeutic application. Bodily introduction of any kind is strictly prohibited by law.
