BPC-157 (Body Protection Compound-157)

Available in 5 mg & 10 mg Lyophilized Vials

The Gold Standard for Tissue Regeneration & Systemic Healing Research

BPC-157 is a synthetic pentadecapeptide (15 amino acids; MW ~1419.55 Da) derived from a protective protein found in human gastric juice. In the field of regenerative medicine research, it has emerged as one of the most versatile and potent compounds available.

Unlike many research peptides that target singular biological pathways, BPC-157 is multimodal. It initiates healing cascades across numerous biological systems, making it an essential tool for investigating complex tissue repair, inflammation modulation, and cytoprotection.

At 4Balance, we provide research-grade BPC-157, verified to ≥99% purity via rigorous HPLC and Mass Spectrometry analysis, ensuring reliable, reproducible data for your laboratory studies.

Key Scientific Mechanisms

BPC-157’s regenerative potential stems from its ability to interact with several critical healing pathways simultaneously:

• Angiogenesis (VEGF Pathway): Stimulates Vascular Endothelial Growth Factor, promoting new blood vessel formation to increase nutrient and oxygen delivery to injured tissues (Seiwerth et al., 2018).

• Growth Factor Modulation: Up regulates signaling of essential repair factors, including EGF, FGF, and TGF-β (Chang et al., 2014).

• Nitric Oxide (NO) Signaling: Enhances local blood flow to injured sites via the NO pathway, facilitating waste removal and nutrient delivery (Sikiric et al., 2016).

• Neurotransmitter Modulation: Influences serotonergic and dopaminergic systems, supporting central nervous system repair and neuroprotection (Park et al., 2022).

Primary Research Applications

1. Musculoskeletal Tissue Regeneration

BPC-157 is widely utilized in orthopedic research models for its exceptional ability to accelerate the healing of stubborn connective tissues.

• Tendon & Ligament: Shown to accelerate type I/III collagen synthesis by 200–300% and increase tensile strength in repaired tendons by up to 60% (Park et al., 2020; Lee et al., 2021).

• Bone Repair: Stimulates osteoblast proliferation and enhances callus formation in critical-size bone defect models (Tohyama et al., 2020).

2. Gastrointestinal (GI) System Protection

Reflecting its gastric origins, BPC-157 exhibits profound cytoprotective effects throughout the digestive tract.

• Ulcer/Mucosal Healing: Demonstrates dramatic reduction (80–90%) in NSAID-induced gastric lesions in animal models (Sikiric et al., 2016).

• Intestinal Barrier ("Leaky Gut"): Upregulates tight junction proteins (ZO-1, occludin) to restore barrier integrity in experimental colitis and sepsis models (Lee et al., 2021).

3. Neurological Protection & Repair

Emerging research indicates significant potential for BPC-157 in neurodegenerative and neurotraumatic models.

• Neuroprotection: Reduces glutamate excitotoxicity by 60–70% and mitigates dopamine neuron loss in Parkinson’s models (Park et al., 2022).

• Nerve Regeneration: Accelerates axonal growth in peripheral nerve injury studies (Kang et al., 2023).

Quality Assurance & Specifications

We understand that purity is paramount for research integrity. Every batch of 4Balance BPC-157 undergoes stringent testing.

• Purity: ≥99% (Reverse-phase HPLC).

• Identity: Confirmed via MALDI-TOF Mass Spectrometry.

• Endotoxins: <0.1 EU/mg (LAL assay).

• Format: Sterile-filtered, lyophilized powder in sealed vials.

• Storage: Stable for 24 months at –20°C in lyophilized form. Once reconstituted, store at 4°C and use within 7 days. Avoid repeated freeze-thaw cycles.

Research Protocol Guidelines

For Laboratory Research Use Only. Not for Human or Veterinary Administration.

Reconstitution: Reconstitute using sterile bacteriostatic water (0.9% benzyl alcohol). Gently swirl to dissolve; do not vortex.

• 5 mg Vial: Add 2.5 mL diluent for ~2 mg/mL concentration.

• 10 mg Vial: Add 5 mL diluent for ~2 mg/mL concentration.

Typical In Vivo Research Dosages (Literature Reference):

• Mice (Tendon): 10–50 μg/kg QD (SC/IP).

• Rats (GI Ulcer): 50–200 μg/kg BID (Oral gavage).

• Comparative Note: BPC-157 often shows superior multi-system activity and oral bioavailability in research models compared to peptides like TB-500 or GHK-Cu.

Ordering Information

• Select Size: Available in 5 mg or 10 mg vials.

• Shipping: Temperature-stable packaging used for all orders. Priority shipping available domestically and internationally.

Complete Disclaimer

This product is sold exclusively for laboratory research purposes (per Section 351 of the Public Health Service Act). It is NOT intended for human or veterinary use, nor for any diagnostic, therapeutic, or cosmetic application. The purchaser certifies that they are appropriately licensed and equipped to handle research chemicals, in compliance with all relevant local, state, and federal regulations. 4Balance Peptides nor 4Balance Fitness assumes no liability for misuse of this product or handling that contravenes the stated purposes. By purchasing this product, you affirm that it will be used for lawful research only.