Epitalon (Epithalon) Peptide

Available in 10mg & 50mg Lyophilized Vials

The Telomerase-Activating Tetrapeptide | Modulator of Cellular Aging & Circadian Rhythms

Product Overview

Epitalon (also known as Epithalon) is a synthetic tetrapeptide consisting of four amino acids (Alanine-Glutamate-Aspartate-Glycine). It is a bio-mimetic of epithalamin, a naturally occurring polypeptide extract from the pineal gland. Originally developed by Professor Vladimir Khavinson, Epitalon has become a primary compound of interest in gerontology and longevity research due to its profound effects on fundamental aging mechanisms.

We offer high-purity, lyophilized Epitalon in flexible 10mg vials for standard protocols and high-concentration 50mg vials for demanding, larger-scale research applications.

Primary Mechanism: Telomerase Activation

The central focus of Epitalon research lies in its ability to influence the Hayflick limit—the number of times a normal human cell population will divide before cell division stops.

Research indicates that Epitalon can upregulate the activity of telomerase, the enzyme responsible for maintaining the length of telomeres (the protective caps at the ends of chromosomes). Telomeres naturally shorten with each cell division, acting as a "biological clock" that eventually leads to cellular senescence. By promoting telomere elongation or slowing their rate of attrition, Epitalon is studied for its potential to extend the replicative lifespan of cells.

Broader Research Applications

Beyond its effects on telomere biology, Epitalon is investigated for its pleiotropic (multi-system) regulatory properties:

• Circadian Rhythm Normalization: As a pineal gland peptide mimetic, research suggests Epitalon influences melatonin synthesis, helping to regulate circadian rhythms and stabilize sleep-wake cycles, particularly in aging models.

• Antioxidant & Neuroprotection: Studies indicate Epitalon possesses strong antioxidant properties, helping to reduce the accumulation of free radicals and lipid peroxidation. This mechanism is currently being researched for potential neuroprotective effects against age-related cognitive decline.

• Immune System Support: In models of immune senescence (aging of the immune system), Epitalon has been shown to stimulate cellular immunity and T-cell function.

Technical Specifications

• Compound Name: Epitalon (Epithalon) tetrapeptide

• Sequence: Ala-Glu-Asp-Gly

• Molecular Formula: C₂₀H₃₄N₆O₉

• Available Sizes: 10mg Vial / 50mg Vial

• Format: Sterile-filtered Lyophilized Powder (requires reconstitution)

• Purity: ≥99% (HPLC Verified)

• Storage: Store lyophilized at -20°C away from light and moisture.

DISCLAIMER: FOR RESEARCH USE ONLY. This product is a laboratory peptide intended strictly for in-vitro and in-vivo research and development. It is not a dietary supplement, drug, or food product. It is strictly NOT approved for human consumption, veterinary use, therapeutic application, or diagnostic use. Bodily introduction of any kind is prohibited by law. Buyer assumes all responsibility for applicable regulations and appropriate use in a research setting.