Ipamorelin

Available in 5mg & 10mg Lyophilized Vials

The Selective Growth Hormone Secretagogue | The "Clean" Agonist

The 4Balance Codex: The Precision Pulse. High-Specificity GH Release without the Cortisol "Spillover".

Product Overview

Ipamorelin is a synthetic pentapeptide and a highly selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS-R1a). In the landscape of growth hormone-releasing peptides (GHRPs), Ipamorelin is the "Gold Standard" for specificity.

Unlike older generations of secretagogues (such as GHRP-6), Ipamorelin is designed to stimulate a potent release of growth hormone without triggering the side effects of significant cortisol, prolactin, or intense hunger spikes.

We offer this compound in two high-concentration formats:

• 5mg Vial: The standard for versatile research protocols.

• 10mg Vial: High-density format for extended studies and efficient stock solution preparation.

Mechanism of Action: The Selective "Gatekeeper"

Ipamorelin functions by mimicking ghrelin, but with a specific affinity profile that makes it unique in research settings:

1. Selective GHS-R1a Activation: It binds to receptors in the pituitary gland to trigger the release of stored growth hormone. This pulse mimics the body's natural, pulsatile secretion pattern.

2. No "Spillover" Effect: The defining characteristic of Ipamorelin is that it does not show affinity for the receptors that signal the release of ACTH (cortisol) or prolactin. This makes it the preferred agent for research aiming to isolate GH effects without the "stress hormone" response.

3. Lipolytic & Anabolic Signaling: By elevating plasma GH levels, Ipamorelin indirectly increases IGF-1 (Insulin-like Growth Factor 1), promoting nitrogen retention (muscle growth) and lipolysis (fat breakdown).

Primary Research Applications

In the 4Balance Research Array, Ipamorelin is utilized for studies requiring a clean endocrine profile:

• Body Composition & Recovery: Investigating the preservation of lean muscle tissue and the acceleration of recovery kinetics following trauma or training stress.

• Anti-Aging & Longevity: Used in models to study the reversal of age-related decline in natural growth hormone production.

• Sleep Architecture: Research suggests Ipamorelin can increase the duration of Stage 4 (Deep Wave) sleep, which is critical for neural and physical repair.

• Bone Density: Studies explore its role in increasing bone mineral density and collagen synthesis without catabolic side effects.

Technical Specifications

• Compound Name: Ipamorelin Acetate

• Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2

• Available Sizes: 5mg Vial / 10mg Vial

• Format: Lyophilized Powder

• Purity: ≥99% (HPLC Verified)

• Solubility: Water Soluble (Requires Bacteriostatic Water).

• Storage: Store lyophilized at -20°C. Protect from light.

DISCLAIMER: FOR LABORATORY RESEARCH USE ONLY. This product is a laboratory reagent intended strictly for in-vitro and in-vivo research and development. It is not for human consumption, veterinary use, anti-aging therapy, or body-building. This product is not a drug, food, or dietary supplement. Bodily introduction of any kind is strictly prohibited by law. Buyer assumes all responsibility for applicable regulations and appropriate use in a research setting.