Melanotan 2 (MT-2)

Available in 10mg Lyophilized Vials

The Cyclic Alpha-MSH Analogue | The Multi-Receptor Agonist

The 4Balance Codex: The Systemic Stimulator. High-Potency Activation of Pigmentary, Metabolic, and Aphrodisiac Pathways.

Product Overview

Melanotan 2 (MT-2) is a synthetic, cyclic analogue of the naturally occurring peptide alpha-Melanocyte Stimulating Hormone (α-MSH).

While it shares the pigmentation capabilities of Melanotan 1, MT-2 is distinct due to its cyclic structure and non-selective binding profile. This structural modification protects it from enzymatic breakdown, making it significantly more potent. We offer this powerful compound in 10mg vials for research exploring the intersection of dermatology, neurobiology, and metabolic regulation.

Mechanism of Action: The Triple-Pathway Agonist

Unlike the selective Melanotan 1, MT-2 is a broad-spectrum agonist that binds with high affinity to multiple melanocortin receptors (MC1R, MC3R, MC4R, MC5R). This results in a "systemic" range of effects:

1. Dermal Pigmentation (MC1R): MT-2 is a potent initiator of melanogenesis. It stimulates melanocytes to produce eumelanin (protective dark pigment) at a rate significantly higher than natural signaling.

2. Libido & CNS Arousal (MC3R / MC4R): MT-2 crosses the blood-brain barrier to bind with receptors in the hypothalamus. This activation is widely researched for its potent aphrodisiac properties and its ability to trigger physiological arousal (erectile function) via the central nervous system.

3. Metabolic Regulation (MC4R): Activation of the MC4 receptor is linked to appetite suppression and increased lipid metabolism. Research subjects often exhibit reduced food intake and enhanced fat oxidation.

Primary Research Applications

In the 4Balance Research Array, Melanotan 2 is utilized when a robust, multi-system response is required:

• Sexual Dysfunction: MT-2 is a primary agent in the study of erectile dysfunction (ED) and female sexual arousal disorder, specifically investigating central (brain-derived) mechanisms of arousal rather than vascular ones.

• Rapid Photoprotection: Investigating the fastest possible induction of eumelanin synthesis for UV protection models.

• Metabolic & Satiety Studies: Exploring the role of the melanocortin system in regulating body weight and caloric intake.

Technical Specifications

• Compound Name: Melanotan II (MT-2)

• Chemical Structure: Cyclic lactam analogue of α-MSH

• Sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH2

• Available Size: 10mg Vial

• Format: Lyophilized Powder

• Purity: ≥99% (HPLC Verified)

• Solubility: Water Soluble (Requires Bacteriostatic Water).

• Storage: Store lyophilized at -20°C. Protect from light.

DISCLAIMER: FOR LABORATORY RESEARCH USE ONLY. This product is a laboratory reagent intended strictly for in-vitro and in-vivo research and development. It is not a cosmetic, drug, dietary supplement, or tanning product. NOT for human consumption, veterinary use, or therapeutic application. Bodily introduction of any kind is strictly prohibited by law. Buyer assumes all responsibility for applicable regulations and appropriate use in a research setting.