YK-11 (Myostine)

Available in 10mg Tablets (100 Count Bottle)

The Myostatin Inhibitor | Steroidal SARM & Follistatin Inducer

The 4Balance Codex: The Genetic Brake-Releaser. A unique synthetic steroid that functions chemically as a SARM. It acts as a gene-selective partial agonist of the androgen receptor to powerfully upregulate the expression of follistatin, which in turn neutralizes myostatin, effectively removing the primary biological limit on muscle differentiation.

Product Overview

YK-11 (Myostine) is a compound that occupies a unique space in anabolic research. While often categorized with SARMs due to its selective effects, chemically, it possesses a steroidal backbone derived from DHT (dihydrotestosterone), making it a "steroidal SARM."

Its primary interest in the scientific community lies not just in its androgenic activity, but in its ability to influence the myostatin pathway—a mechanism distinct from traditional anabolic agents. 4Balance Peptides offers this complex research agent in precise, laboratory-grade 10mg tablets, providing superior accuracy for dosing protocols compared to liquid suspensions.

Mechanism of Action: The Follistatin-Myostatin Axis

YK-11’s mechanism is multi-faceted and distinct from standard non-steroidal SARMs. Its primary value in research stems from its ability to manipulate the genetic governors of muscle growth:

1. Gene-Selective Partial Agonism: Research indicates that YK-11 binds to the androgen receptor (AR) but acts as a "gene-selective partial agonist." It does not activate the receptor in the same way as testosterone; instead, it triggers specific transcriptional pathways in target tissues.

2. Follistatin Induction (Myostatin Inhibition): The most significant outcome of YK-11’s specific AR binding is the potent induction of follistatin expression. Follistatin is a naturally occurring glycoprotein that acts as an antagonist to myostatin. Myostatin is a protein that naturally inhibits muscle growth (a "brake" on muscle mass). By increasing follistatin, YK-11 causes the follistatin to bind to and neutralize myostatin, effectively lifting the "brake" on muscle development.

3. Enhanced Myogenic Differentiation: In-vitro studies (notably Kanno et al.) using C2C12 myoblast cells demonstrated that YK-11 accelerates myogenic differentiation—the process where muscle precursor cells mature into functional muscle fibers—more effectively than DHT itself. This suggests a potent ability to drive the creation of new muscle tissue architecture.

4. Osteoblastic Activity: Like many androgenic compounds, YK-11 has been observed in cell culture studies to stimulate osteoblast (bone-building cell) activity, indicating potential research applications for bone mineral density.

Primary Research Applications

In the 4Balance Research Array, YK-11 is a specialized agent for studies focused on novel anabolic pathways:

• Myostatin Pathway Modulation: Investigating the effects of inhibiting myostatin via upregulation of endogenous follistatin to overcome genetic limitations on muscle accrual.

• Muscle Wasting Disorders: Studying novel approaches to treating severe sarcopenia or dystrophy where traditional anabolic pathways may be insufficient.

• Bone Physiology: Exploring the potential of steroidal SARMs to improve bone density via increased osteoblast proliferation.

Technical Specifications

• Compound Name: YK-11 (Myostine)

• Chemical Structure: Synthetic Steroidal SARM (DHT derivative)

• Format: Oral Tablets

• Concentration: 10mg per Tablet

• Quantity: 100 Tablets

• Purity: ≥99% (HPLC Verified)

• Storage: Store at room temperature, away from direct light and moisture.

DISCLAIMER: FOR LABORATORY RESEARCH USE ONLY. This product is a laboratory chemical intended strictly for in-vitro and in-vivo research and development. It is not a drug, dietary supplement, or treatment for any medical condition. NOT for human consumption, veterinary use, or therapeutic application. Bodily introduction of any kind is strictly prohibited by law. Buyer assumes all responsibility for applicable regulations and appropriate use in a research setting.